Structure of PDB 5eyz Chain D

Receptor sequence
>5eyzD (length=92) Species: 9606 (Homo sapiens) [Search protein sequence]
DNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNE
GDQVVLINGRDIAEHTHDQVVLFIKASCERHSGELMLLVRPN
3D structure
PDB5eyz Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
ChainD
Resolution2.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D R527 F528 G529 F530 N531 V532 K533 Q538 S545 H579 D580 V583 I586 R15 F16 G17 F18 N19 V20 K21 Q26 S33 H67 D68 V71 I74
External links
PDB RCSB:5eyz, PDBe:5eyz, PDBj:5eyz
PDBsum5eyz
PubMed27246854
UniProtP29074|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)

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