Structure of PDB 5efj Chain D

Receptor sequence
>5efjD (length=356) Species: 7955 (Danio rerio) [Search protein sequence]
PITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPA
RLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTC
ALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAAL
TARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGA
FFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAR
EFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIIL
EGGYNLTSISESMSMCTSMLLGDSPPSLHLTPLKTSATVSINNVLRAHAP
FWSSLR
3D structure
PDB5efj Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
ChainD
Resolution1.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.98: histone deacetylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D S531 P571 H573 H574 G582 F583 D612 H614 F643 E742 G743 Y745 S90 P130 H132 H133 G141 F142 D171 H173 F202 E301 G302 Y304
BS02 ZN D D612 H614 D705 D171 H173 D264
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