Structure of PDB 5dnc Chain D

Receptor sequence
>5dncD (length=356) Species: 10141 (Cavia porcellus) [Search protein sequence]
ERHLLLIYTGGALGMQSKGGVLVPGPGLVTLLRTLPMFHDKEFAQAQGLP
DHALALPPASHGPRVLYTVLECQPLLDSSDMTIDDWIRIAKIIERHYEQY
QGFVVIHGTDTMASGASMLSFMLENLHKPVILTGAQVPIRVLWNDARENL
LGALLVAGQYIIPEVCLFMNSQLFRGNRVTKVDSQKFEAFCSPNLSPLAT
VGADVTIAWDLVRKVKWKDPLVVHSNMEHDVALLRLYPGIPASLVRAFLQ
PPLKGVVLETFGSGNGPSKPDLLQELRAAAQRGLIMVNCSQCLRGSVTPG
YATSLAGANIVSGLDMTSEAALAKLSYVLGLPELSLERRQELLAKDLRGE
MTLPTA
3D structure
PDB5dnc Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases.
ChainD
Resolution2.01 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A19 V28 T116 D117 K188
Catalytic site (residue number reindexed from 1) A12 V21 T109 D110 K181
Enzyme Commision number 3.5.1.1: asparaginase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASN D A19 D84 S85 G115 T116 D117 A142 A12 D77 S78 G108 T109 D110 A135
Gene Ontology
Molecular Function
GO:0004067 asparaginase activity
Biological Process
GO:0009066 aspartate family amino acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5dnc, PDBe:5dnc, PDBj:5dnc
PDBsum5dnc
PubMed26733195
UniProtH0W0T5

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