Structure of PDB 5dn2 Chain D

Receptor sequence
>5dn2D (length=156) Species: 9606 (Homo sapiens) [Search protein sequence]
MFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLD
SNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWM
VYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLE
LFGCRV
3D structure
PDB5dn2 Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket.
ChainD
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D Y299 W304 T319 D323 S349 T352 Y356 G417 I418 Y26 W31 T46 D50 S76 T79 Y83 G144 I145
BS02 peptide D R303 T305 Q307 E351 R30 T32 Q34 E78
External links
PDB RCSB:5dn2, PDBe:5dn2, PDBj:5dn2
PDBsum5dn2
PubMed26991001
UniProtO60462|NRP2_HUMAN Neuropilin-2 (Gene Name=NRP2)

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