Structure of PDB 5dg3 Chain D

Receptor sequence
>5dg3D (length=249) Species: 381754 (Pseudomonas aeruginosa PA7) [Search protein sequence]
LIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKI
GKHNRIYQFSSVGEDTPPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGD
HNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYC
RIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIH
ALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR
3D structure
PDB5dg3 Structures of Pseudomonas aeruginosa LpxA Reveal the Basis for Its Substrate Selectivity.
ChainD
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H121 D122 G139
Catalytic site (residue number reindexed from 1) H112 D113 G130
Enzyme Commision number 2.3.1.129: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U21 D M114 N133 F166 N194 E196 R200 M105 N124 F157 N185 E187 R191
Gene Ontology
Molecular Function
GO:0008780 acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0008610 lipid biosynthetic process
GO:0009245 lipid A biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5dg3, PDBe:5dg3, PDBj:5dg3
PDBsum5dg3
PubMed26352800
UniProtA6V1E4|LPXA_PSEA7 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (Gene Name=lpxA)

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