Structure of PDB 5dg1 Chain D

Receptor sequence

>5dg1D (length=129) Species: 9606 (Homo sapiens)

ELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSES
TIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHEL
TFPNRLGHSHLSYLSVRGGFNMSSFKLKE

3D structure

• PDB: 5dg1 Human galectin-2 interacts with carbohydrates and peptides non-classically: new insight from X-ray crystallography and hemagglutination.
• Chain: D
• Resolution: 3.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GAL	D	H48 R52 W68 E71	H42 R46 W62 E65

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0016936 galactoside binding
• GO:0030246 carbohydrate binding

Biological Process

• GO:0043029 T cell homeostasis
• GO:0043065 positive regulation of apoptotic process
• GO:0050729 positive regulation of inflammatory response
• GO:0098609 cell-cell adhesion

Cellular Component

• GO:1990724 galectin complex

External links

• PDB: RCSB:5dg1, PDBe:5dg1, PDBj:5dg1
• PDBsum: 5dg1
• PubMed: 27563008
• UniProt: P05162|LEG2_HUMAN Galectin-2 (Gene Name=LGALS2)