Structure of PDB 5d0j Chain D

Receptor sequence
>5d0jD (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
AIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCH
LQKVKHYLILPSEEERLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLR
HCCT
3D structure
PDB5d0j Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D R438 R462 N463 K478 H479 Y480 L481 M495 R15 R39 N40 K55 H56 Y57 L58 M71
External links
PDB RCSB:5d0j, PDBe:5d0j, PDBj:5d0j
PDBsum5d0j
PubMed27257138
UniProtQ14451|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)

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