Structure of PDB 5bs0 Chain D

Receptor sequence
>5bs0D (length=197) Species: 9606 (Homo sapiens) [Search protein sequence]
AQEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLYV
RPYQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVRPGGAGPF
FVVFGKGTKLSVIPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQ
SKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIP
3D structure
PDB5bs0 Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
ChainD
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y32 A98 Y31 A97
Gene Ontology
Biological Process
GO:0002250 adaptive immune response
GO:0009617 response to bacterium
Cellular Component
GO:0005886 plasma membrane
GO:0042101 T cell receptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5bs0, PDBe:5bs0, PDBj:5bs0
PDBsum5bs0
PubMed26758806
UniProtA0A0B4J279;
P01848|TRAC_HUMAN T cell receptor alpha chain constant (Gene Name=TRAC)

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