Structure of PDB 5brm Chain D

Receptor sequence
>5brmD (length=144) Species: 9606 (Homo sapiens) [Search protein sequence]
DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWKCSA
PKYIDYLMTWVQDQLDDETLFPFPKNFMSVAKTILKRLFRVYAHIYHQHF
DSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL
3D structure
PDB5brm Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
ChainD
Resolution2.651 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D R92 Y93 E94 Y95 H96 R157 Y163 F167 M171 E176 R199 E200 E206 L207 R41 Y42 E43 Y44 H45 R90 Y96 F100 M104 E109 R132 E133 E139 L140
BS02 peptide D A58 V59 V62 F65 N66 N69 L126 D127 A7 V8 V11 F14 N15 N18 L65 D66
BS03 ZN D C79 C84 H161 H166 C28 C33 H94 H99
External links
PDB RCSB:5brm, PDBe:5brm, PDBj:5brm
PDBsum5brm
PubMed26108669
UniProtQ9H8S9|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)

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