Structure of PDB 5bqq Chain D

Receptor sequence
>5bqqD (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPGH
3D structure
PDB5bqq Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
ChainD
Resolution1.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D H5 G8 S9 V12 E13 Y16 G23 F24 F25 Y26 H5 G8 S9 V12 E13 Y16 G23 F24 F25 Y26
BS02 peptide D C7 L11 L15 V18 C19 R22 G23 F24 C7 L11 L15 V18 C19 R22 G23 F24
BS03 peptide D F1 V2 F1 V2
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:5bqq, PDBe:5bqq, PDBj:5bqq
PDBsum5bqq
PubMed26792393
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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