Structure of PDB 5b4w Chain D

Receptor sequence
>5b4wD (length=436) Species: 9606 (Homo sapiens) [Search protein sequence]
PPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPV
LDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRR
LGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYT
SIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAY
FLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAA
AVATSVAHGEVLFAAFSSAAPGASALCAFPLDEVDRLANRTRDACYTREG
RAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEAT
PILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQ
SIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVAS
3D structure
PDB5b4w Allosteric Inhibition of a Semaphorin 4D Receptor Plexin B1 by a High-Affinity Macrocyclic Peptide
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D S241 R245 E269 G270 R272 T351 P391 S212 R216 E240 G241 R243 T306 P346
BS02 peptide D Q240 S241 F294 T395 P396 I397 E399 D414 G415 H416 T417 L433 G434 S437 Q211 S212 F263 T350 P351 I352 E354 D369 G370 H371 T372 L388 G389 S392
Gene Ontology
Molecular Function
GO:0017154 semaphorin receptor activity
Biological Process
GO:0071526 semaphorin-plexin signaling pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:5b4w, PDBe:5b4w, PDBj:5b4w
PDBsum5b4w
PubMed27984026
UniProtO43157|PLXB1_HUMAN Plexin-B1 (Gene Name=PLXNB1)

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