Structure of PDB 5a6b Chain D

Receptor sequence
>5a6bD (length=616) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence]
SMVRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQ
LTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLN
VASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEI
EAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVY
DLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNGVVDRSLLMCQHL
ERVLDIADKYGFHCQMWSDMFFKMSIPEETRVYLDRLKDRVTLVYWDYYQ
DSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKAC
RANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKT
NTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTP
EQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQ
AYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDI
RMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATT
ANQWHTIATASTIYTT
3D structure
PDB5a6b A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
ChainD
Resolution1.77 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OAN D R94 W266 W306 Y308 Y309 W339 W373 D375 R95 W267 W296 Y298 Y299 W329 W363 D365 MOAD: Ki=7.9nM
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0015929 hexosaminidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5a6b, PDBe:5a6b, PDBj:5a6b
PDBsum5a6b
PubMed26491009
UniProtA0A0H2US73

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