Structure of PDB 4zvs Chain D

Receptor sequence
>4zvsD (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
YKIPVEADFLFAYSTVPGYASMRNPGRGSWFVQALCSILEEHGKDLEIMQ
ILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
3D structure
PDB4zvs Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
ChainD
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D S531 M532 R533 N534 P535 S575 Q576 S21 M22 R23 N24 P25 S65 Q66
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4zvs, PDBe:4zvs, PDBj:4zvs
PDBsum4zvs
PubMed27032039
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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