Structure of PDB 4znx Chain D

Receptor sequence
>4znxD (length=57) Species: 9606 (Homo sapiens) [Search protein sequence]
TLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIP
SNYVAPV
3D structure
PDB4znx The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
ChainD
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D F87 S114 D118 W120 S135 P140 F3 S30 D34 W36 S51 P56
BS02 peptide D Y91 Y93 D100 E116 G117 D118 W119 N136 Y137 Y7 Y9 D16 E32 G33 D34 W35 N52 Y53
External links
PDB RCSB:4znx, PDBe:4znx, PDBj:4znx
PDBsum4znx
PubMed27599862
UniProtP06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)

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