Structure of PDB 4z87 Chain D

Receptor sequence
>4z87D (length=484) Species: 284811 (Eremothecium gossypii ATCC 10895) [Search protein sequence]
TYRDAATALEHLATYAEKDGLSVEQLMDGGLTYNDFLVLPGKIDFPSSEV
VLSSRLTKKITLNAPFVSSPMDTVTEADMAIHMALLGGIGIIHHNCTAEE
QAEMVRRVKKYENGFINAPVVVGPDATVADVRRMKNEFGFAGFPVTDDGK
PTGKLQGIITSRDIQFVEDETLLVSEIMTKDVITGKQGINLEEANQILKN
TKKGKLPIVDEAGCLVSMLSRTDLMKNQSYPLASKSADTKQLLCGAAIGT
IDADRQRLAMLVEAGLDVVVLDSSQGNSVFQINMIKWIKETFPDLQVIAG
NVVTREQAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQ
FANQFGVPCIADGGVQNIGHITKAIALGASTVMMGGMLAGTTESPEYFFR
DGKRLKTYRGMGSAQGVTGSVIDKGSIKKYIPYLYNGLQHSCQDIGVRSL
VEFREKVDSGSVRFEFRTPSAQLEGGVHNLHSYE
3D structure
PDB4z87 Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases.
ChainD
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0005524 ATP binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006177 GMP biosynthetic process
GO:0006183 GTP biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4z87, PDBe:4z87, PDBj:4z87
PDBsum4z87
PubMed26558346
UniProtQ756Z6

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