Structure of PDB 4z7n Chain D

Receptor sequence
>4z7nD (length=469) Species: 9606 (Homo sapiens) [Search protein sequence]
NICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPE
SIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSI
QVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIG
FGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTR
FNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDA
KTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQK
NINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIR
SKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAK
VRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGN
GTFECGVCRCGPGWLGSQC
3D structure
PDB4z7n beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece.
ChainD
Resolution2.599 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D S121 Y122 S123 N215 R216 A218 S119 Y120 S121 N213 R214 A216
BS02 MN D S121 E220 S119 E218
BS03 MN D S123 M124 D126 D127 M335 S121 M122 D124 D125 M333
BS04 MN D D158 N215 D217 A218 P219 E220 D156 N213 D215 A216 P217 E218
External links
PDB RCSB:4z7n, PDBe:4z7n, PDBj:4z7n
PDBsum4z7n
PubMed26631735
UniProtP05106|ITB3_HUMAN Integrin beta-3 (Gene Name=ITGB3)

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