Structure of PDB 4y00 Chain D

Receptor sequence
>4y00D (length=77) Species: 9606 (Homo sapiens) [Search protein sequence]
TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF
TEYETQVKVMSQRHMIGGRWCDCKLPN
3D structure
PDB4y00 Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
ChainD
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D S163 Q164 S61 Q62
BS02 dna D D105 K136 F149 L177 P178 N179 D3 K34 F47 L75 P76 N77
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:4y00, PDBe:4y00, PDBj:4y00
PDBsum4y00
PubMed26883171
UniProtQ13148|TADBP_HUMAN TAR DNA-binding protein 43 (Gene Name=TARDBP)

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