Structure of PDB 4xoq Chain D

Receptor sequence
>4xoqD (length=198) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
ELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHHTRPTRFVW
LQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQILYDAPEVVI
PMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAVRGLGSCWIG
STIFAADLVRDELDLPVDWEPLGAIAIGYADEPSGLRDPVPADLLILK
3D structure
PDB4xoq Elongation of the Poly-gamma-glutamate Tail of F420 Requires Both Domains of the F420: gamma-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis.
ChainD
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.8.17: dehydro coenzyme F420 reductase.
6.3.2.31: coenzyme F420-0:L-glutamate ligase.
6.3.2.34: coenzyme F420-1:gamma-L-glutamate ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F42 D M313 W317 D320 I398 S400 F403 M64 W68 D71 I149 S151 F154 MOAD: Kd=1.47uM
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016881 acid-amino acid ligase activity

View graph for
Molecular Function
External links
PDB RCSB:4xoq, PDBe:4xoq, PDBj:4xoq
PDBsum4xoq
PubMed26861878
UniProtP9WP79|FBIB_MYCTU Bifunctional F420 biosynthesis protein FbiB (Gene Name=fbiB)

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