Structure of PDB 4xlo Chain D

Receptor sequence
>4xloD (length=461) Species: 115828 (Streptomyces maritimus) [Search protein sequence]
QFPQLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARC
TSTPDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIK
VSRRLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFG
WLSRKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVV
TAFEFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLR
LAPPLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKA
TLPYRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPF
TQLELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWA
REGYRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTN
LFRLNQNIPPS
3D structure
PDB4xlo Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
ChainD
Resolution1.67 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H78 S137 T245
Catalytic site (residue number reindexed from 1) H77 S136 T244
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD D W37 V73 R74 G75 G76 G77 H78 S79 M80 H83 S84 L94 G134 V135 V136 G140 G142 G143 L144 L146 F150 V200 V201 Y416 N418 N456 W36 V72 R73 G74 G75 G76 H77 S78 M79 H82 S83 L93 G133 V134 V135 G139 G141 G142 L143 L145 F149 V199 V200 Y415 N417 N455
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0042802 identical protein binding
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding

View graph for
Molecular Function
External links
PDB RCSB:4xlo, PDBe:4xlo, PDBj:4xlo
PDBsum4xlo
PubMed24162851
UniProtQ9KHK2

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