Structure of PDB 4xev Chain D

Receptor sequence
>4xevD (length=147) Species: 9606 (Homo sapiens) [Search protein sequence]
LDRTDDLVYLNVMELVRAVLELKNELSQLPPEGYVVVVKNVGLTLRKLIG
SVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEEA
KRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHGMEELDALLEELER
3D structure
PDB4xev Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats.
ChainD
Resolution2.0073 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D K911 G914 L917 R918 D925 N947 M957 K39 G42 L45 R46 D53 N75 M85
Gene Ontology
Molecular Function
GO:0004713 protein tyrosine kinase activity
Biological Process
GO:0006468 protein phosphorylation
GO:0007172 signal complex assembly
Cellular Component
GO:0005925 focal adhesion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xev, PDBe:4xev, PDBj:4xev
PDBsum4xev
PubMed26866573
UniProtQ14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta (Gene Name=PTK2B)

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