Structure of PDB 4xco Chain D

Receptor sequence

>4xcoD (length=93) Species: 2190 (Methanocaldococcus jannaschii)

DAIMRGKFTLNELMTQLEAIENMGSMKLTEAKIKKYKVIISSMTKEEREN
PKIIKASRIRRIARGSGTTENDVREVLRYYETTKNAIDKLRKG

3D structure

• PDB: 4xco Signal-sequence induced conformational changes in the signal recognition particle.
• Chain: D
• Resolution: 2.9 Å

Enzymatic activity

• Enzyme Commision number: 3.6.5.4: signal-recognition-particle GTPase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	V375 S378 S379 M380 T381 K382 S394 R395 R398 G402 S403 G404	V38 S41 S42 M43 T44 K45 S57 R58 R61 G65 S66 G67

Gene Ontology

Molecular Function

• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0008312 7S RNA binding

Biological Process

• GO:0006614 SRP-dependent cotranslational protein targeting to membrane

Cellular Component

• GO:0048500 signal recognition particle

External links

• PDB: RCSB:4xco, PDBe:4xco, PDBj:4xco
• PDBsum: 4xco
• PubMed: 26051119
• UniProt: Q57565|SRP54_METJA Signal recognition particle 54 kDa protein (Gene Name=srp54)