Structure of PDB 4x3t Chain D

Receptor sequence
>4x3tD (length=62) Species: 10090 (Mus musculus) [Search protein sequence]
HMGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLV
MAYEEKEERDRA
3D structure
PDB4x3t Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
ChainD
Resolution2.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 45E D V10 F11 W32 W35 Y39 V6 F7 W28 W31 Y35 MOAD: Kd=28.9uM
BS02 45E D H47 I48 H43 I44 MOAD: Kd=28.9uM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4x3t, PDBe:4x3t, PDBj:4x3t
PDBsum4x3t
PubMed25660273
UniProtQ8VDS3|CBX7_MOUSE Chromobox protein homolog 7 (Gene Name=Cbx7)

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