Structure of PDB 4wrk Chain D

Receptor sequence
>4wrkD (length=153) Species: 12360 (Dubowvirus dv11) [Search protein sequence]
NTLQVRLLSENARMPERNHKTDAGYDIFSAETVVLEPQEKAVIKTDVAVS
IPEGYVGLLTSRSGVSSKTHLVIETGKIDAGYHGNLGINIKNNAIASNGY
ITPGVFDIKGEIDLSDAIRQYGTYQINEGDKLAQLVIVPIWTPELKQVEE
FES
3D structure
PDB4wrk The 3D structure of D95N mutant DUTPase from phage phi11 of S. aureus reveals the molecular details for the coordination of a structural Mg(II) ion
ChainD
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A25 R64 G66 L73 D81
Catalytic site (residue number reindexed from 1) A23 R62 G64 L71 D79
Enzyme Commision number 3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DUP D R64 S65 Q136 R62 S63 Q134
BS02 DUP D G78 K79 I80 D81 Y84 G89 G76 K77 I78 D79 Y82 G87
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004170 dUTP diphosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006226 dUMP biosynthetic process
GO:0046081 dUTP catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4wrk, PDBe:4wrk, PDBj:4wrk
PDBsum4wrk
PubMed
UniProtQ8SDV3

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