Structure of PDB 4wj7 Chain D

Receptor sequence
>4wj7D (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
IEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAV
LSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQACC
LVILAAESKVAAEELCCLLGQVF
3D structure
PDB4wj7 Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations.
ChainD
Resolution2.753 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D P82 S83 S84 R85 H137 I139 A140 A141 V142 S143 Y144 R146 E207 F217 P20 S21 S22 R23 H75 I77 A78 A79 V80 S81 Y82 R84 E113 F123
External links
PDB RCSB:4wj7, PDBe:4wj7, PDBj:4wj7
PDBsum4wj7
PubMed25525273
UniProtQ9BSQ5|CCM2_HUMAN Cerebral cavernous malformations 2 protein (Gene Name=CCM2)

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