Structure of PDB 4urm Chain D

Receptor sequence
>4urmD (length=190) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
EAARKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDN
WIKVTDNGRGIPVDIQEKMGRPAVEVILTVLHAGVGSSVVNALSQDLEVY
VHRNETIYHQAYKKGVPQFDLKEVGTTDKTGTVIRFKADGEIFTETTVYN
YETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEG
3D structure
PDB4urm Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode.
ChainD
Resolution2.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XAM D N54 E58 D81 R84 I86 I102 V105 H107 A108 T173 I175 N29 E33 D56 R59 I61 I77 V80 H82 A83 T132 I134
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:4urm, PDBe:4urm, PDBj:4urm
PDBsum4urm
PubMed24992706
UniProtP0A0K8|GYRB_STAAU DNA gyrase subunit B (Gene Name=gyrB)

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