Structure of PDB 4um9 Chain D

Receptor sequence
>4um9D (length=455) Species: 9606 (Homo sapiens) [Search protein sequence]
GCALGGAETCEDCLLIGPQCAWCATENERCDTPANLLAKGCQLNFIENPV
SQVEILKNKPLSVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTE
DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVE
KPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKN
QKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMD
SKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFA
VTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEV
LGDTEGLNLSFTAICNNGTLFQHQKKCSHMKVGDTASFSVTVNIPHCERR
SRHIIIKPVGLGDALELLVSPECNCDCQKVEVNSSKCHNGNGSFQCGVCA
CPRCE
3D structure
PDB4um9 Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
ChainD
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D G5 C6 S125 A126 Y185 A217 N218 I219 T221 E223 G1 C2 S113 A114 Y173 A205 N206 I207 T209 E211
BS02 MG D S125 E223 S113 E211
BS03 CA D S127 D130 D131 K338 S115 D118 D119 K326
BS04 CA D E162 N218 D220 P222 E223 E150 N206 D208 P210 E211
External links
PDB RCSB:4um9, PDBe:4um9, PDBj:4um9
PDBsum4um9
PubMed25383667
UniProtP18564|ITB6_HUMAN Integrin beta-6 (Gene Name=ITGB6)

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