Structure of PDB 4uc5 Chain D

Receptor sequence
>4uc5D (length=347) Species: 487 (Neisseria meningitidis) [Search protein sequence]
HHYPTDDIKIKEVKELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGR
DKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRT
TVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITP
QYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAI
GAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAA
EQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVM
VESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR
3D structure
PDB4uc5 Calculated Pka Variations Expose Dynamic Allosteric Communication Networks.
ChainD
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN D C63 H270 E304 D324 C61 H268 E302 D322
BS02 PHE D Q153 A156 L181 S182 F211 S213 Q151 A154 L179 S180 F209 S211
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:4uc5, PDBe:4uc5, PDBj:4uc5
PDBsum4uc5
PubMed26794122
UniProtQ9K169

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