Structure of PDB 4u7u Chain D

Receptor sequence
>4u7uD (length=191) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
AWMYLSKVIIARAWSRDLYQLHQGLWHLFPDFLFHVEKRNTPEGCHVLLQ
SAQMPVSTAVATVIKTKQVEFQLQVGVPLYFRLRANPIKTILDNQKRLDS
KGNIKRCRVPLIKEAEQIAWLQRKLGNAARVEDVHPISERPQYFSKSGKI
QTVCFEGVLTINDAPALIDLVQQGIGPAKSMGCGLLSLAPL
3D structure
PDB4u7u Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli
ChainD
Resolution3.003 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna D K94 T95 I96 D98 N99 Q100 R102 R111 C112 R113 P115 I117 R128 K129 S155 K157 I158 Q159 K187 S188 K89 T90 I91 D93 N94 Q95 R97 R106 C107 R108 P110 I112 R123 K124 S147 K149 I150 Q151 K179 S180
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0005515 protein binding
Biological Process
GO:0006396 RNA processing
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4u7u, PDBe:4u7u, PDBj:4u7u
PDBsum4u7u
PubMed25118175
UniProtQ46897|CAS6_ECOLI CRISPR system Cascade subunit CasE (Gene Name=casE)

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