Structure of PDB 4tzc Chain D

Receptor sequence
>4tzcD (length=107) Species: 10090 (Mus musculus) [Search protein sequence]
TSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKASNL
NLIGRPSTVHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLT
RSALLPT
3D structure
PDB4tzc Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex
ChainD
Resolution1.88 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EF2 D Y357 E360 W382 Y37 E40 W62
BS02 ZN D C325 C328 C393 C396 C5 C8 C73 C76
BS03 EF2 D H380 S381 W382 W388 W402 F404 H60 S61 W62 W68 W82 F84
External links
PDB RCSB:4tzc, PDBe:4tzc, PDBj:4tzc
PDBsum4tzc
PubMed
UniProtQ8C7D2|CRBN_MOUSE Protein cereblon (Gene Name=Crbn)

[Back to BioLiP]