Structure of PDB 4tvw Chain D

Receptor sequence
>4tvwD (length=337) Species: 562 (Escherichia coli) [Search protein sequence]
STLRLLISDSYDPWFNLAVAECIFRQMPATQRVLFLWRNADTVVIGRAQN
PWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIS
TSIVLNALNALGVSAEASGRNDLVVKTVEGDRKVSGSAYRETKDRGAHGG
TLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVC
EAITEAFFAHYGERVEAEIISPNKTPDLPNFAETFARQSSWEWNFGQAPA
FSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGC
LYRADMLQQECEALLVDFPEQEKELRELSAWMAGAVR
3D structure
PDB4tvw Computational design of a red fluorophore ligase for site-specific protein labeling in living cells.
ChainD
Resolution3.505 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.1.20: lipoate--protein ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 37P D W37 R70 S72 G75 A76 V77 F78 H79 K133 G136 S137 A138 T151 L153 L161 V180 W37 R70 S72 G75 A76 V77 F78 H79 K133 G136 S137 A138 T151 L153 L161 V180
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016979 lipoate-protein ligase activity
GO:0017118 lipoyltransferase activity
Biological Process
GO:0009249 protein lipoylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4tvw, PDBe:4tvw, PDBj:4tvw
PDBsum4tvw
PubMed25313043
UniProtP32099|LPLA_ECOLI Lipoate-protein ligase A (Gene Name=lplA)

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