Structure of PDB 4tlm Chain D

Receptor sequence
>4tlmD (length=753) Species: 8355 (Xenopus laevis) [Search protein sequence]
MDIAVILVGTTEEVAIKDVHEKDDFHHLPVTPRVELVTMQESDPKSIITR
ICDLMSDKKVQGVVFGDDTDQEAIAQILDFISVQTLTPILGIHGGSSMIM
ADKEEASMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFEN
KVRSTIENSFVGWELEEVIHLDMSLDDIDSKIQNQLCKLQSPVILLYCTK
EEATYIFEVAHSVGLTGYGFTWIVPSLVAGDTDTVPDEFPTGLISVSYDE
WDYDLPARVRDGIAIITTAASTMLSEHNSIPQSKSSCNNIQESRVYEAHM
LKRYLINVTFEGRDLSFSEDGYQMHPKLVIILLNQERKWERVGKYKDRSL
KMWEHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIIKRCCKGFCI
DILKKIAKTVKFTYDLYLVTNGKHGKKINGVWNGMIGEVVTKRAYMAVGS
LTINEERSEVVDFSVPFIETGISVMVSRSNGSAFLEPFSADVWVMMFVML
LIVSAVAVFVFEFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWAF
FAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVP
NGSTERNIRNNYLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLN
YMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDG
EMEELEALWLTGICHNEKSQLDIDNMAGVFYMLAAAMALSLITFIMEHLF
YKS
3D structure
PDB4tlm NMDA receptor structures reveal subunit arrangement and pore architecture.
ChainD
Resolution3.77 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QEM D Q105 I106 F109 Y170 F171 Q76 I77 F80 Y141 F142
BS02 JEG D H479 L506 T507 S673 H424 L451 T452 S603
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0038023 signaling receptor activity
Biological Process
GO:0006811 monoatomic ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4tlm, PDBe:4tlm, PDBj:4tlm
PDBsum4tlm
PubMed25008524
UniProtA7XY94|NMDE2_XENLA Glutamate receptor ionotropic, NMDA 2B (Gene Name=grin2b)

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