Structure of PDB 4rrf Chain D

Receptor sequence
>4rrfD (length=139) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence]
MKMLLIHSDYLEFEAKEKTKIAEETENLKGKLDECLACFIAVEREDENNP
EGTAIGAVEEIEKVANQLKVNNIVVYPYAHLSSDLSSPETAVKVLKDIES
ILKERGYNVLRAPFGWYKAFKISCKGHPLSELSRKIVAK
3D structure
PDB4rrf Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
ChainD
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.3: threonine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A3S D I25 V46 Y82 L89 A95 F118 G119 I21 V42 Y78 L85 A91 F114 G115 MOAD: Kd=239.2uM
PDBbind-CN: -logKd/Ki=3.62,Kd=239.2uM
Gene Ontology
Molecular Function
GO:0004829 threonine-tRNA ligase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4rrf, PDBe:4rrf, PDBj:4rrf
PDBsum4rrf
PubMed26113036
UniProtQ58597|SYT_METJA Threonine--tRNA ligase (Gene Name=thrS)

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