Structure of PDB 4r74 Chain D

Receptor sequence
>4r74D (length=319) Species: 715 (Actinobacillus pleuropneumoniae) [Search protein sequence]
SKGRLVIYCSATNVMCENAAKTFEQKYDVKTSFIRNGSGSTFAKIEAEKN
NPQADVWYGGTLDPQSQAGELGLLEAYRSPNIDQIMPKFQDPAKVKGNLS
SAVYIGILGFAVNTERLKKLGIEKIPQCWNDLTDPKLKGEIQIADPQSSG
TAYTAIATFAQLWGEDKAFDYFKHLHPNISQYTKSGITPARNAARGETTV
GIGFLHDYALEKEQGAPLEMVVPCEGTGYELGGVSILKGARNLDNAKLFV
DFALSKEGQETAWKKGQALQTLTNTTAEQSPLAFDLTKLKLIDYDFEKYG
ASDERKRLINKWVDEIKLA
3D structure
PDB4r74 Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen.
ChainD
Resolution1.93 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F6P D T11 S37 G59 Y103 S148 G149 T150 G185 I186 H205 D206 E229 T12 S38 G60 Y104 S149 G150 T151 G186 I187 H206 D207 E230 MOAD: Kd=8nM
BS02 MG D N241 D243 N244 N242 D244 N245
Gene Ontology
Molecular Function
GO:0030975 thiamine binding
GO:0030976 thiamine pyrophosphate binding
Biological Process
GO:0015888 thiamine transport
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4r74, PDBe:4r74, PDBj:4r74
PDBsum4r74
PubMed26295949
UniProtA3N294

[Back to BioLiP]