Structure of PDB 4r3u Chain D

Receptor sequence
>4r3uD (length=129) Species: 391953 (Aquincola tertiaricarbonis) [Search protein sequence]
TPIRVLLAKVGLDGHDRGVKVVARALRDAGMDVIYSGLHRTPEEVVNTAI
QEDVDVLGVSLLSGVQLTVFPKIFKLLDERGAGDLIVIAGGVMPDEDAAA
IRKLGVREVLLQDTPPQAIIDSIRSLVAA
3D structure
PDB4r3u Structural basis of the stereospecificity of bacterial B12-dependent 2-hydroxyisobutyryl-CoA mutase.
ChainD
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K12 D16 H18
Catalytic site (residue number reindexed from 1) K9 D13 H15
Enzyme Commision number 5.4.99.64: 2-hydroxyisobutanoyl-CoA mutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 B12 D G17 H18 D19 R20 G21 V25 G61 S63 L65 A92 G93 G94 L113 L114 Q115 T117 I122 G14 H15 D16 R17 G18 V22 G58 S60 L62 A89 G90 G91 L110 L111 Q112 T114 I119
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0031419 cobalamin binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4r3u, PDBe:4r3u, PDBj:4r3u
PDBsum4r3u
PubMed25720495
UniProtI3VE74|HCMB_AQUTE 2-hydroxyisobutanoyl-CoA mutase small subunit (Gene Name=hcmB)

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