Structure of PDB 4r2n Chain D

Receptor sequence
>4r2nD (length=353) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
VTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDT
VNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVG
DEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLI
FVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSL
GLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSS
IGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVW
LPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWR
SDQ
3D structure
PDB4r2n Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities
ChainD
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PHE D Y54 F246 Y54 F246
BS02 PLP D G84 S85 V86 F110 N157 D184 A186 Y187 T214 S216 K217 R225 G84 S85 V86 F110 N157 D184 A186 Y187 T214 S216 K217 R225
BS03 PHE D Y15 E111 R322 Y15 E111 R322
Gene Ontology
Molecular Function
GO:0004400 histidinol-phosphate transaminase activity
GO:0008483 transaminase activity
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0000105 L-histidine biosynthetic process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4r2n, PDBe:4r2n, PDBj:4r2n
PDBsum4r2n
PubMed26738801
UniProtP9WML5|PATR_MYCTU Putative phenylalanine aminotransferase (Gene Name=pat)

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