Structure of PDB 4q5f Chain D

Receptor sequence
>4q5fD (length=206) Species: 6253 (Ascaris suum) [Search protein sequence]
MPQYKLTYFDIRGLGEGARLIFHQAGVKFEDNRLKREDWPALKPKTPFGQ
LPLLEVDGEVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMA
ELRPCFRVLAGFEEGDKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVG
KSVTWADLVITDSLASWESLIPDFLSGHLQLKKYIEHVRELPNIKKWIAE
RPKTPY
3D structure
PDB4q5f Crystal Structure of the Glutathione S-transferase from Ascaris lumbricoides
ChainD
Resolution2.448 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) L109
Catalytic site (residue number reindexed from 1) L109
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH D F9 L14 W39 K43 Q50 L51 Q63 S64 F9 L14 W39 K43 Q50 L51 Q63 S64
BS02 GSH D P104 C105 P104 C105
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0004602 glutathione peroxidase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm
GO:0005903 brush border

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4q5f, PDBe:4q5f, PDBj:4q5f
PDBsum4q5f
PubMed
UniProtP46436|GST1_ASCSU Glutathione S-transferase 1 (Gene Name=GST1)

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