Structure of PDB 4q30 Chain D

Receptor sequence
>4q30D (length=258) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKL
TIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFS
KPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIA
VFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR
KPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNK
WWYDKGEC
3D structure
PDB4q30 Thermodynamics and mechanism of the interaction of willardiine partial agonists with a glutamate receptor: implications for drug development.
ChainD
Resolution2.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NWD D E13 Y61 L90 T91 R96 L138 G141 S142 T143 T174 L192 E193 M196 E10 Y58 L87 T88 R93 L135 G138 S139 T140 T171 L189 E190 M193
BS02 ZN D H23 E24 H20 E21
BS03 ZN D E42 H46 E39 H43
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4q30, PDBe:4q30, PDBj:4q30
PDBsum4q30
PubMed24850223
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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