Structure of PDB 4pxi Chain D

Receptor sequence
>4pxiD (length=193) Species: 1902 (Streptomyces coelicolor) [Search protein sequence]
EQTRATIIGAAADLFDRRGYESTTLSEIVAHAGVTKGALYFHFAAKEDLA
HAILEIQSRTSRRLAKDLDYSSLEALMRLTFGMARLCVQGPVLRAGLRLA
TAGVPVRLPHPFTEWREIATSRLLDAVRQSDVHQDIDVDSVAHTLVCSVV
GTRVAGREPRRLAEMWYILIRGMVPVTRRARYVTLAARLEQET
3D structure
PDB4pxi Structural and functional basis of transcriptional regulation by TetR family protein CprB from S. coelicolor A3(2)
ChainD
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D T31 L32 K43 Y47 A52 K53 T24 L25 K36 Y40 A45 K46 PDBbind-CN: Kd=200nM
BS02 dna D T42 G44 A45 T35 G37 A38 PDBbind-CN: Kd=200nM
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4pxi, PDBe:4pxi, PDBj:4pxi
PDBsum4pxi
PubMed25092919
UniProtO66122

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