Structure of PDB 4oa5 Chain D

Receptor sequence
>4oa5D (length=213) Species: 212042 (Anaplasma phagocytophilum str. HZ) [Search protein sequence]
LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMA
GIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCK
LEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRK
GGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTII
PTSEGMMVSIKLT
3D structure
PDB4oa5 An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilum.
ChainD
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D136 K139 D162 N163
Catalytic site (residue number reindexed from 1) D131 K134 D157 N158
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH D Q39 L40 G64 C66 S70 E88 K89 E116 A117 D136 N138 Q34 L35 G59 C61 S65 E83 K84 E111 A112 D131 N133
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
Biological Process
GO:0008150 biological_process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4oa5, PDBe:4oa5, PDBj:4oa5
PDBsum4oa5
PubMed26544981
UniProtQ2GKC7

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