Structure of PDB 4mtz Chain D

Receptor sequence
>4mtzD (length=77) Species: 9606 (Homo sapiens) [Search protein sequence]
EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVD
RWQYGDSAVGRHRKVSPNCRFINGFYL
3D structure
PDB4mtz Protein-protein interactions in nfkb pathway: novel tools to promote apoptosis in cancer therapy
ChainD
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C3063 C3066 H3083 C3090 C42 C45 H62 C69
BS02 0BU D R3062 C3066 H3067 S3087 P3088 N3089 R41 C45 H46 S66 P67 N68
External links
PDB RCSB:4mtz, PDBe:4mtz, PDBj:4mtz
PDBsum4mtz
PubMed
UniProtP98170|XIAP_HUMAN E3 ubiquitin-protein ligase XIAP (Gene Name=XIAP)

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