Structure of PDB 4mky Chain D

Receptor sequence
>4mkyD (length=284) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QRVTLTNADKVLYPATGTTKSDIFDYYAGVAEVMLGHIAGRPATRKRWPN
GVDQPAFFEKQLALSAPPWLSRATVAHRSGTTTYPIIDSATGLAWIAQQA
ALEVHVPQWRFVAEPGSGELNPGPATRLVFDLDPGEGVMMAQLAEVARAV
RDLLADIGLVTFPVTSGSKGLHLYTPLDEPVSSRGATVLAKRVAQRLEQA
MPALVTSTMTKSLRAGKVFVDWSQNSGSKTTIAPYSLRGRTHPTVAAPRT
WAELDDPALRQLSYDEVLTRIARDGDLLERLDAD
3D structure
PDB4mky Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase.
ChainD
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.5.1.1: DNA ligase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D N16 K29 R56 P58 F66 S74 Q107 N7 K20 R47 P49 F57 S65 Q98
BS02 dna D M218 K220 R223 D230 M209 K211 R214 D221
BS03 dna D F66 F67 K69 R87 S88 F57 F58 K60 R78 S79
External links
PDB RCSB:4mky, PDBe:4mky, PDBj:4mky
PDBsum4mky
PubMed24239356
UniProtP9WNV3|LIGD_MYCTU Multifunctional non-homologous end joining DNA repair protein LigD (Gene Name=ligD)

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