Structure of PDB 4mjl Chain D

Receptor sequence
>4mjlD (length=339) Species: 543734 (Lacticaseibacillus casei BL23) [Search protein sequence]
MVVKVGVIGTGAMGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRDFHL
NAKVYPDDTSLLQDPDIDAVFVVSFGGAHEATVLKALDTDKFIFTEKPLA
TTLEGAKRIVDKELTKSKKVIQVGFMRRYDQGIRALKEKLDTGIIGAPLV
VRASHINPNVASNYSNEMAITDTLIHEIDEMHWLLDDEYTSIQITYPRQS
AEVRNEGLHDPQLATLTTKKGTVIQVLVHVTAQYGYEVKLEVIGETGELQ
LPNYGLGPILRSNANQQTAVEMSWINRFIQAYNTEVQEFIDEVAKSEPPV
GPSAWDGYIAAITAAAANRSQKDQETVLINVAGTPTFYQ
3D structure
PDB4mjl Crystal Structure of myo-inositol dehydrogenase from Lactobacillus casei in complex with NAD and D-chiro-inositol
ChainD
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K97
Catalytic site (residue number reindexed from 1) K97
Enzyme Commision number 1.1.1.18: inositol 2-dehydrogenase.
1.1.1.369: D-chiro-inositol 1-dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD D G11 A12 M13 D35 I36 V73 S74 H79 E96 K97 M126 D172 W274 Y282 G11 A12 M13 D35 I36 V73 S74 H79 E96 K97 M126 D172 W274 Y282
BS02 CBU D K97 H155 N157 D172 T173 H176 Y236 K97 H155 N157 D172 T173 H176 Y236
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0050112 inositol 2-dehydrogenase (NAD+) activity
Biological Process
GO:0019310 inositol catabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4mjl, PDBe:4mjl, PDBj:4mjl
PDBsum4mjl
PubMed
UniProtA0A0J9X1Y2

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