Structure of PDB 4mbe Chain D

Receptor sequence
>4mbeD (length=149) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
LNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREIL
DLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGK
ISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAICTDS
3D structure
PDB4mbe Structural basis for binding the TREX2 complex to nuclear pores, GAL1 localisation and mRNA export.
ChainD
Resolution2.612 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D Q23 Y26 Q11 Y14
BS02 CA D D142 D144 D146 E148 E153 D130 D132 D134 E136 E141
BS03 CA D D33 N35 D37 F39 E44 D21 N23 D25 F27 E32
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0006406 mRNA export from nucleus
GO:0030474 spindle pole body duplication
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048193 Golgi vesicle transport
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005816 spindle pole body
GO:0005825 half bridge of spindle pole body
GO:0005856 cytoskeleton
GO:0044732 mitotic spindle pole body
GO:0070390 transcription export complex 2

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4mbe, PDBe:4mbe, PDBj:4mbe
PDBsum4mbe
PubMed24705649
UniProtP06704|CDC31_YEAST Cell division control protein 31 (Gene Name=CDC31)

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