Structure of PDB 4m63 Chain D

Receptor sequence
>4m63D (length=361) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
VAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHKDSYVGDEAQSKRG
ILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPK
ANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTV
PIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIK
EKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQ
PSFLGMEACGIHETTYNSIMKCAAAIRKDLYANTVLSGGTTMYPGIADRM
QKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYD
ESGPSIVHRKC
3D structure
PDB4m63 The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
ChainD
Resolution2.748 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP D G13 S14 G15 M16 K18 G156 D157 V159 K213 E214 G301 G302 M305 Y306 K336 G9 S10 G11 M12 K14 G143 D144 V146 K200 E201 G288 G289 M292 Y293 K323
BS02 CA D D11 Q137 D7 Q124
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000281 mitotic cytokinesis
GO:0006338 chromatin remodeling
GO:0007291 sperm individualization
GO:0030723 ovarian fusome organization
GO:0032507 maintenance of protein location in cell
GO:0035148 tube formation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0031011 Ino80 complex
GO:0035060 brahma complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4m63, PDBe:4m63, PDBj:4m63
PDBsum4m63
PubMed24120140
UniProtP10987|ACT1_DROME Actin-5C (Gene Name=Act5C)

[Back to BioLiP]