Structure of PDB 4lmg Chain D

Receptor sequence
>4lmgD (length=120) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSACP
FRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKND
EKAIKTFDELEYKASLNLPL
3D structure
PDB4lmg Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2.
ChainD
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna D R76 S80 K81 Y117 S118 V119 R35 S39 K40 Y57 S58 V59
BS02 dna D K58 V73 I74 E75 R76 S77 R87 S88 K17 V32 I33 E34 R35 S36 R46 S47
BS03 ZN D C86 C109 H133 H135 C45 C49 H73 H75
BS04 ZN D D53 H55 D12 H14
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Biological Process
GO:0010106 cellular response to iron ion starvation
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:4lmg, PDBe:4lmg, PDBj:4lmg
PDBsum4lmg
PubMed24591629
UniProtQ08957|AFT2_YEAST Iron-regulated transcriptional activator AFT2 (Gene Name=AFT2)

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