Structure of PDB 4lg2 Chain D

Receptor sequence
>4lg2D (length=122) Species: 386032 (Reston ebolavirus - Reston (1989)) [Search protein sequence]
ISAKDLKEIMYDHLPGFGTAFHQLVQVICKIGKDNNLLDTIHAEFQASLA
DGDSPQCALIQITKRVPIFQDVPPPIIHIRSRGDIPRACQKSLRPAPPSP
KIDRGWVCLFKMQDGKTLGLKI
3D structure
PDB4lg2 Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism.
ChainD
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna D C264 I267 Q268 K271 R311 C57 I60 Q61 K64 R104 PDBbind-CN: Kd=0.1uM
BS02 rna D F228 Q263 F21 Q56 PDBbind-CN: Kd=0.1uM
External links
PDB RCSB:4lg2, PDBe:4lg2, PDBj:4lg2
PDBsum4lg2
PubMed23824825
UniProtQ8JPY0|VP35_EBORR Polymerase cofactor VP35 (Gene Name=VP35)

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