Structure of PDB 4knl Chain D

Receptor sequence
>4knlD (length=204) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence]
LPKYKPQVNSSINDYICKNNLKAPKIEEDYTSYFPKYAYRNGVGRPEGIV
VHDTANDRSTINGEISYMKNNYQNAFVHAFVDGDRIIETAPTDYLSWGVG
AVGNPRFINVEIVHTHDYASFARSMNNYADYAATQLQYYGLKPDSAEYDG
NGTVWTHYAVSKYLGGTDHADPHGYLRSHNYSYDQLYDLINEKYLIKMGK
VAPW
3D structure
PDB4knl Structure-function analysis of Staphylococcus aureus amidase reveals the determinants of peptidoglycan recognition and cleavage.
ChainD
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.96: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase.
3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D N287 W310 G311 G313 H370 T380 H382 N74 W97 G98 G100 H157 T167 H169
BS02 MUB D T267 N269 E277 E324 H382 T54 N56 E64 E111 H169
Gene Ontology
Molecular Function
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
Biological Process
GO:0009253 peptidoglycan catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4knl, PDBe:4knl, PDBj:4knl
PDBsum4knl
PubMed24599952
UniProtQ2FZK7|ATL_STAA8 Bifunctional autolysin (Gene Name=atl)

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