Structure of PDB 4jol Chain D

Receptor sequence
>4jolD (length=60) Species: 9606 (Homo sapiens) [Search protein sequence]
IDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELN
YWIRRYSDAE
3D structure
PDB4jol A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
ChainD
Resolution2.906 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D S522 V525 S34 V37
BS02 peptide D I489 H491 E501 H504 L505 H507 L508 I1 H3 E13 H16 L17 H19 L20
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4jol, PDBe:4jol, PDBj:4jol
PDBsum4jol
PubMed23812588
UniProtQ06455|MTG8_HUMAN Protein CBFA2T1 (Gene Name=RUNX1T1)

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