Structure of PDB 4j8r Chain D

Receptor sequence

>4j8rD (length=220) Species: 10090 (Mus musculus) [Search protein sequence]

VKLQESGGEVVRPGTSVKVSCKASGYAFTNYLIEWVKQRPGQGLEWIGVI
NPGSGDTNYNEKFKGKATLTADKSSSTAYMQLNSLTSDDSAVYFCARSGA
AAPTYYAMDYWGQGVSVTVSSAKTTPPSVYPLAPAAAAANSMVTLGCLVK
GYFPEPVTVTWNSGSLSGGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETV
TCNVAHPASSTKVDKKIVPR

3D structure

PDB

4j8r The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody.

Chain

Resolution

2.303 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	D	Y32 N58 G96 A97 P100 T100A Y100B Y100C A100D D101	Y31 N58 G99 A100 P103 T104 Y105 Y106 A107 D109

External links

PDB	RCSB:4j8r, PDBe:4j8r, PDBj:4j8r
PDBsum	4j8r
PubMed	23629842

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