Structure of PDB 4ix2 Chain D

Receptor sequence
>4ix2D (length=333) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence]
MLRIAKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMD
TVTEARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVKISGGLRVGAAVGA
APGNEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGG
NVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAG
VANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVIL
YQGRSYKAYRGMPEGIEGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVE
DLRTKAQFVRISGAGMKESHVHDVQITKEAPNY
3D structure
PDB4ix2 Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, complexed with IMP.
ChainD
Resolution2.146 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP D M51 G304 S305 I306 C307 D340 G341 V362 G363 S364 Y387 G389 M390 E417 M49 G176 S177 I178 C179 D212 G213 V234 G235 S236 Y259 G261 M262 E264
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4ix2, PDBe:4ix2, PDBj:4ix2
PDBsum4ix2
PubMed
UniProtQ9KTW3

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